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Int J Occup Med Environ Health ; 34(1): 133-138, 2021 Jan 07.
Artigo em Inglês | MEDLINE | ID: mdl-33223540

RESUMO

Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock, and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors' knowledge, this is the second case of a morphine-related CS reported in literature. Int J Occup Med Environ Health. 2021;34(1):133-8.


Assuntos
Analgésicos Opioides/efeitos adversos , Morfina/intoxicação , Choque Cardiogênico/induzido quimicamente , Disfunção Ventricular Esquerda/induzido quimicamente , Administração Intravenosa/efeitos adversos , Adulto , Analgésicos Opioides/administração & dosagem , Humanos , Hipotensão/induzido quimicamente , Masculino , Morfina/administração & dosagem , Naloxona/uso terapêutico , Antagonistas de Entorpecentes/uso terapêutico , Norepinefrina/uso terapêutico , Tentativa de Suicídio , Função Ventricular Esquerda
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